Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879447 | 0.91 | POLB (0.41) | ALDH1A1KMT2ALMNAPOLBP2RX7 | |
| SCHEMBL8877150 | 0.90 | POLB (0.39) | ALDH1A1KMT2ALMNAPOLBP2RX7 | |
| SCHEMBL8877501 | 0.89 | MDM2 (0.39) | ALDH1A1KMT2ALMNAPOLBP2RX7 | |
| SCHEMBL8877111 | 0.88 | ALDH1A1 (0.37) | ALDH1A1KMT2ALMNAPOLBP2RX7 | |
| SCHEMBL8876027 | 0.85 | POLB (0.36) | ALDH1A1KMT2ALMNAPOLBCTSS | |
| SCHEMBL8877333 | 0.83 | SMN1; SMN2 (0.38) | ALDH1A1KMT2ALMNAPOLBP2RX7 | |
| SCHEMBL8877593 | 0.82 | TSHR (0.42) | ALDH1A1KMT2ALMNAPOLBP2RX7 | |
| SCHEMBL8317180 | 0.82 | CYP3A4 (0.35) | ALDH1A1KMT2ALMNAPOLBP2RX7 | |
| SCHEMBL8876386 | 0.80 | CTSS (0.40) | ALDH1A1KMT2ALMNACTSSCTSK | |
| SCHEMBL9727473 | 0.80 | FKBP1A (0.47) | ALDH1A1KMT2APOLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |