Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | TDO2 | P48775 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | KLK1 | P06870 | 2/20 | 0.46 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465257 | 0.86 | RAB9A (0.59) | RAB9ANPC1IDO1TDO2LMNA | |
| SCHEMBL9639259 | 0.85 | HSP90AB1 (0.69) | RAB9ANPC1IDO1TDO2LMNA | |
| SCHEMBL31320843 | 0.82 | RAB9A (0.70) | RAB9ANPC1IDO1TDO2LMNA | |
| SCHEMBL4225391 | 0.82 | RAB9A (0.70) | RAB9ANPC1IDO1TDO2LMNA | |
| SCHEMBL8464964 | 0.82 | RAB9A (0.70) | RAB9ANPC1IDO1TDO2LMNA | |
| SCHEMBL9637017 | 0.82 | IDO1 (0.61) | RAB9ANPC1IDO1TDO2LMNA | |
| SCHEMBL24763383 | 0.81 | HSP90AB1 (0.50) | RAB9ANPC1IDO1TDO2LMNA | |
| SCHEMBL3174922 | 0.80 | NPC1 (0.66) | RAB9ANPC1IDO1TDO2LMNA | |
| SCHEMBL7942570 | 0.77 | NPC1 (0.62) | RAB9ANPC1IDO1TDO2LMNA | |
| SCHEMBL7809188 | 0.76 | HTT (0.66) | RAB9ANPC1IDO1TDO2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693627-A | TREATING DISEASES SUCH AS LEUKEMIAS AND LYMPHOMAS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-12-02 | — | — | US | disclosed |