Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.61 |
| ▸ | TDO2 | P48775 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | KLK1 | P06870 | 2/20 | 0.43 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582961 | 0.83 | IDO1 (0.58) | IDO1TDO2RAB9ANPC1KMT2A | |
| SCHEMBL8876085 | 0.82 | RAB9A (0.66) | IDO1TDO2RAB9ANPC1KMT2A | |
| SCHEMBL31320843 | 0.78 | RAB9A (0.70) | IDO1TDO2RAB9ANPC1KMT2A | |
| SCHEMBL4225391 | 0.78 | RAB9A (0.70) | IDO1TDO2RAB9ANPC1KMT2A | |
| SCHEMBL8464964 | 0.78 | RAB9A (0.70) | IDO1TDO2RAB9ANPC1KMT2A | |
| SCHEMBL1890826 | 0.77 | RAB9A (0.59) | IDO1TDO2RAB9ANPC1KMT2A | |
| SCHEMBL13648923 | 0.77 | IDO1 (0.59) | IDO1TDO2RAB9ANPC1KMT2A | |
| SCHEMBL3174922 | 0.76 | NPC1 (0.66) | IDO1TDO2RAB9ANPC1KMT2A | |
| SCHEMBL135979 | 0.74 | CA12 (0.69) | IDO1TDO2RAB9ANPC1KMT2A | |
| SCHEMBL9639259 | 0.74 | HSP90AB1 (0.69) | IDO1TDO2RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082849-A | Antiinflammatory agents or antiallergens | AVENTIS PHARMACEUTICALS INC. | 1992-01-21 | — | — | US | disclosed |
| EP-0434827-A4 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | — | 1992-01-08 | — | — | EP | disclosed |
| EP-0434827-A1 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1991001123-A2 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-02-07 | — | — | WO | disclosed |
| US-4977162-A | Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments | RORER PHARMACEUTICAL CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |