Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | EIF4E | P06730 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808649 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TDP1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6650948 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TDP1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL3224897 | 0.83 | KMT2A (0.55) | ALDH1A1TDP1MAPTL3MBTL1HTT | |
| SCHEMBL25087329 | 0.77 | L3MBTL1 (0.57) | ALDH1A1TDP1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1319057 | 0.77 | MAPT (0.55) | ALDH1A1TDP1MAPTL3MBTL1HTT | |
| Methyl Alcohol SCHEMBL27388373 | 0.77 | KMT2A (0.53) | ALDH1A1TDP1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6425266 | 0.76 | ALDH1A1 (0.72) | ALDH1A1TDP1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8403658 | 0.76 | EIF4E (0.53) | ALDH1A1TDP1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL3600729 | 0.75 | CA12 (0.65) | ALDH1A1TDP1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL13011426 | 0.75 | VCAM1 (0.53) | ALDH1A1TDP1MAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693646-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |