Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.39 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.38 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.38 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.38 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696696 | 0.75 | LTB4R (0.44) | LMNANPC1RAB9AALDH1A1PDE10A | |
| SCHEMBL4188279 | 0.74 | RAB9A (0.42) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL5839896 | 0.73 | ALDH1A1 (0.54) | LMNANPC1KMT2AMRGPRX4ALDH1A1 | |
| SCHEMBL9429117 | 0.71 | TOP2A (0.43) | LMNADCPSMRGPRX4ALDH1A1POLB | |
| SCHEMBL8332290 | 0.70 | GUCY1B2 (0.32) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1MRGPRX4 | |
| SCHEMBL8333267 | 0.70 | RAB9A (0.41) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL14917525 | 0.67 | DHODH (0.53) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL9330379 | 0.66 | PDE10A (0.44) | DHFRLMNAMEN1KMT2APOLB | |
| SCHEMBL27802771 | 0.66 | PDE10A (0.50) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL7590081 | 0.66 | PDE10A (0.58) | LMNAMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593845-A | BY REACTION WITH PEROXIDES AND PEROXIDASE; DETECTION OF HAPTENS, PROTEINS, ANTIBODIES IN ENZYME IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-01-14 | — | — | US | disclosed |