Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | FNTA | P49354 | 6/20 | 0.36 |
| ▸ | FNTB | P49356 | 6/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457894 | 0.83 | MAPK1 (0.53) | MAPK1SMN1; SMN2DRD4DRD2FNTA | |
| SCHEMBL32668926 | 0.83 | MAPK1 (0.53) | MAPK1SMN1; SMN2DRD4DRD2FNTA | |
| SCHEMBL8878095 | 0.79 | DRD4 (0.39) | MAPK1SMN1; SMN2DRD4DRD2HTR2A | |
| SCHEMBL8876923 | 0.78 | FNTA (0.43) | MAPK1SMN1; SMN2DRD4DRD2HTR2A | |
| SCHEMBL7000885 | 0.76 | FNTA (0.45) | MAPK1SMN1; SMN2DRD4DRD2HTR2A | |
| SCHEMBL9215850 | 0.75 | DRD2 (0.41) | MAPK1SMN1; SMN2DRD4DRD2HTR2A | |
| SCHEMBL5475539 | 0.72 | HRH1 (0.54) | MAPK1SMN1; SMN2HTR2AFNTAFNTB | |
| SCHEMBL8709456 | 0.71 | MAPK1 (0.72) | MAPK1SMN1; SMN2DRD2HTR2AHRH1 | |
| SCHEMBL9215632 | 0.71 | HTR2A (0.36) | MAPK1SMN1; SMN2DRD4DRD2HTR2A | |
| SCHEMBL9832235 | 0.70 | MAPK1 (0.53) | MAPK1SMN1; SMN2DRD4DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665726-A | ANTIALLERGIC, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0685476-A1 | Benzo(5,6)cycloheptapyridines, compositions and methods of use | SCHERING CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5438062-A | Antiallergens, antiinflammatory agents | SCHERING CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0270818-B1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORP (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0288640-B1 | 6,11-Dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta-[1,2-b]pyridines and compositions and methods of use | SCHERING CORPORATION (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5089496-A | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies | SCHERING CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0330673-A1 | BENZO 5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4804666-A | ANTIHISTAMINES | SCHERING CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0288640-A1 | 6,11-Dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta-[1,2-b]pyridines and compositions and methods of use | SCHERING CORPORATION (US) | 1988-11-02 | — | — | EP | disclosed |
| EP-0270818-A1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988003138-A1 | BENZO[5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1988-05-05 | — | — | WO | disclosed |