Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 9/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846712 | 0.78 | CA2 (0.45) | CA2PPARGKCNH2FFAR1PPARA | |
| SCHEMBL4089575 | 0.74 | MAPT (0.50) | CA2PPARGKCNH2FFAR1MAPT | |
| SCHEMBL9838039 | 0.70 | SLC2A1 (0.40) | MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL8218339 | 0.70 | ALDH1A1 (0.52) | CA2PPARGKCNH2FFAR1MAPT | |
| SCHEMBL9839454 | 0.69 | SLC2A1 (0.38) | MAPT | |
| SCHEMBL9839418 | 0.69 | HPGD (0.34) | KDM4EHPGD | |
| SCHEMBL9570635 | 0.68 | MAPT (0.53) | CA2PPARGKCNH2FFAR1PPARA | |
| SCHEMBL9838017 | 0.68 | PTGS1 (0.37) | — | |
| SCHEMBL30079867 | 0.67 | POLB (0.46) | MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL13846717 | 0.67 | CA2 (0.47) | CA2PPARGKCNH2FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594016-A | ANTIDIABETIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0604983-B1 | Naphthalene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-11-20 | — | — | EP | disclosed |
| EP-0604983-A1 | Naphthalene derivatives | Mitsubishi Chemical Corporation (JP) | 1994-07-06 | — | — | EP | disclosed |