Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877405 | 0.85 | NSD2 (0.35) | CNR2EPHX2BCHEGRM1 | |
| SCHEMBL8876687 | 0.85 | EPHX2 (0.33) | CNR2EPHX2BCHEGRM1 | |
| SCHEMBL15279044 | 0.85 | HTR2A (0.43) | CNR2EPHX2BCHEGRM1 | |
| SCHEMBL8877357 | 0.85 | CNR2 (0.33) | CNR2EPHX2BCHEGRM1 | |
| SCHEMBL8876558 | 0.77 | GRM1 (0.37) | CNR2EPHX2BCHEGRM1 | |
| SCHEMBL8876593 | 0.77 | KEAP1 (0.39) | CNR2HSD11B1BCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL8875976 | 0.77 | ALDH1A1 (0.38) | CNR2HSD11B1BCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL8877363 | 0.76 | GRM1 (0.33) | CNR2HSD11B1BCHEGRM1ALDH1A1 | |
| SCHEMBL8877389 | 0.75 | KEAP1 (0.41) | CNR2HSD11B1BCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL8875969 | 0.75 | KEAP1 (0.41) | CNR2HSD11B1BCHEALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130253185-A1 | NOVEL CATALYSTS | DALHOUSIE UNIVERSITY (CA) | 2013-09-26 | — | — | US | disclosed |
| US-20130253185-A1 | NOVEL CATALYSTS | DALHOUSIE UNIVERSITY (CA) | 2013-09-26 | — | — | US | disclosed |
| WO-2012068335-A2 | NOVEL CATALYSTS | DALHOUSIE UNIVERSITY (CA) | 2012-05-24 | — | — | WO | disclosed |