SCHEMBL887730

SCHEMBL887730

CCCCCC1(OC=O)CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSL P07711 3/20 0.34
CTSB P07858 3/20 0.34
CTSK P43235 3/20 0.34
CETP P11597 4/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887734 0.98 CETP (0.35) CTSLCTSBCTSKCETPMEN1
SCHEMBL887782 0.98 CETP (0.35) CTSLCTSBCTSKCETPMEN1
SCHEMBL887760 0.98 CETP (0.35) CTSLCTSBCTSKCETPMEN1
SCHEMBL8018226 0.96 TSHR (0.34) CTSLCTSBCTSKCETPMEN1
SCHEMBL887669 0.94 CTSL (0.35) CTSLCTSBCTSKCETPMEN1
SCHEMBL4674998 0.92 MEN1 (0.35) CTSLCTSBCTSKCETPMEN1
SCHEMBL4353688 0.90 TSHR (0.33) TSHR
SCHEMBL28697362 0.89 TSHR (0.37) SIRT2TSHR
SCHEMBL18697320 0.86 CTSL (0.32) CTSLCTSBCTSK
SCHEMBL887736 0.86 CTSL (0.32) CTSLCTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040259-B2 Production of polyketides and other natural products BUCK INSTITUTE FOR RESEARCH ON AGING (US) 2015-05-26 US claimed
US-20110165633-A1 Production of Polyketides and Other Natural Products BUCK INSTITUTE FOR RESEARCH ON AGING 2011-07-07 US claimed
US-20080287482-A1 Production of Polyketides and Other Natural Products GREGORY MATTHEW ALAN 2008-11-20 US claimed
EP-1967520-A2 Production of polyketides and other natural products Biotica Technology Limited (GB) 2008-09-10 EP claimed
EP-1589031-B1 Production of polyketides and other natural products BIOTICA TECH LTD (GB) 2007-08-15 EP claimed
EP-1655372-A2 Production of polyketides and other natural products Biotica Technology Limited (GB) 2006-05-10 EP claimed
US-20050272132-A1 Production of polyketides and other natural products BIOTICA TECHNOLOGY LIMITED (GB) 2005-12-08 US claimed
EP-1589031-A2 Production of polyketides and other natural products Biotica Technology Limited (GB) 2005-10-26 EP claimed
EP-1521828-A2 PRODUCTION OF POLYKETIDES Biotica Technology Limited (GB) 2005-04-13 EP claimed
WO-2004007709-A2 PRODUCTION OF POLYKETIDES BIOTICA TECHNOLOGY LIMITED (GB) 2004-01-22 WO claimed
US-5811475-A REACTING A CARBON WITH A POLYMER HAVING A REACTIVE GROUP AND A HYDROLYZABLE TERT-ALKYL ACRYLIC ESTER; PRINTING INKS; DIELECTRICS; HIGH ELECTRICAL RESISTANCE NIPPON OIL CO., LTD. (JP) 1998-09-22 US claimed
CN-109070206-A The engagement manufacturing method of copper thickener, the manufacturing method of conjugant and semiconductor device 日立化成株式会社 2018-12-21 CN disclosed
CN-108795444-A Liquid crystal compound with negative dielectric anisotropy and preparation method and application thereof 烟台丰蓬液晶材料有限公司 2018-11-13 CN disclosed
CN-108517216-A Liquid crystal compound with negative dielectric anisotropy and preparation method and application thereof 烟台丰蓬液晶材料有限公司 2018-09-11 CN disclosed
CN-104955984-B Sliding member and method for manufacturing same 日产自动车株式会社 2018-06-12 CN disclosed
WO-2004007709-A2 PRODUCTION OF POLYKETIDES BIOTICA TECHNOLOGY LIMITED (GB) 2004-01-22 WO disclosed
US-5821277-A Thermosetting and procuring compositions for color filters and method for making the same NIPPON OIL CO., LTD. (JP) 1998-10-13 US disclosed
US-5811475-A REACTING A CARBON WITH A POLYMER HAVING A REACTIVE GROUP AND A HYDROLYZABLE TERT-ALKYL ACRYLIC ESTER; PRINTING INKS; DIELECTRICS; HIGH ELECTRICAL RESISTANCE NIPPON OIL CO., LTD. (JP) 1998-09-22 US disclosed
EP-0753548-A2 Method for producing carbonaceous material NIPPON OIL COMPANY, LIMITED (JP) 1997-01-15 EP disclosed
EP-0423520-A2 Liquid crystalline composition for the use in a twisted nematic cell MERCK PATENT GmbH (DE) 1991-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080287482-A1 Production of Polyketides and Other Natural Products FKBP14, FKBP4, FKBP2 CTSL 2203/4885CTSB 2453/4885CTSK 1020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.