⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880017 | 0.69 | — | — | |
| SCHEMBL8877670 | 0.68 | TUBB4A (0.30) | — | |
| SCHEMBL8879377 | 0.60 | — | — | |
| SCHEMBL10900576 | 0.59 | MAOA (0.36) | — | |
| SCHEMBL8879372 | 0.58 | HSD17B10 (0.47) | — | |
| SCHEMBL28829617 | 0.58 | MAOA (0.36) | — | |
| SCHEMBL5494021 | 0.56 | CDC25B (0.41) | — | |
| SCHEMBL1501865 | 0.56 | CDC25B (0.41) | — | |
| SCHEMBL9007427 | 0.55 | — | — | |
| SCHEMBL18032691 | 0.54 | GSK3A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | claimed |
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | disclosed |