Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007340 | 0.86 | HSD17B10 (0.46) | HSD17B10PKMALDH1A1GAAHTT | |
| SCHEMBL11024449 | 0.74 | HSD17B10 (0.71) | HSD17B10PKMALDH1A1GAAHTT | |
| SCHEMBL8877670 | 0.74 | TUBB4A (0.30) | ALDH1A1LMNAPOLBHPGDKDM4E | |
| SCHEMBL8879355 | 0.69 | PKM (0.33) | PKMALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10900576 | 0.68 | MAOA (0.36) | HTTLMNAPOLBNPC1KDM4E | |
| SCHEMBL28829617 | 0.66 | MAOA (0.36) | HTTLMNAPOLBNPC1KDM4E | |
| SCHEMBL8437480 | 0.65 | PKM (1.00) | HSD17B10PKMALDH1A1GAAHTT | |
| SCHEMBL7738030 | 0.65 | ALDH1A1 (0.79) | HSD17B10PKMALDH1A1GAAHTT | |
| SCHEMBL1501865 | 0.62 | CDC25B (0.41) | HSD17B10PKMALDH1A1GAAHTT | |
| SCHEMBL8258013 | 0.62 | PKM (0.49) | HSD17B10PKMALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | claimed |
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | disclosed |