Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026814 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1KMT2AMEN1S100A4 | |
| SCHEMBL435178 | 0.76 | NOTUM (0.33) | ALDH1A1KMT2AMEN1PTPRCMAPT | |
| SCHEMBL13827494 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TDP1KMT2AMEN1S100A4 | |
| SCHEMBL13418991 | 0.72 | TDP1 (0.59) | ALDH1A1TDP1KMT2AMEN1S100A4 | |
| SCHEMBL2075134 | 0.72 | TDP1 (0.45) | ALDH1A1TDP1KMT2AMEN1S100A4 | |
| SCHEMBL15380368 | 0.71 | S100A4 (0.56) | ALDH1A1TDP1KMT2AMEN1S100A4 | |
| SCHEMBL8986646 | 0.71 | CYP2A6 (0.38) | ALDH1A1TDP1TP53CYP1A2CYP2C9 | |
| SCHEMBL30535903 | 0.71 | ALDH1A1 (0.74) | ALDH1A1TDP1KMT2AMEN1S100A4 | |
| SCHEMBL1287837 | 0.71 | ALDH1A1 (0.74) | ALDH1A1TDP1KMT2AMEN1S100A4 | |
| SCHEMBL10337930 | 0.71 | ALDH1A1 (0.57) | ALDH1A1TDP1KMT2AMEN1S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688791-A | COMPOUNDS FOR TREATMENNT OF VIRAL DISEASES SUCH AS AIDS | UBE INDUSTRIES, LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |