Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494621 | 0.84 | CA1 (0.34) | PDK2CA1CA2CA7CA9 | |
| SCHEMBL8986646 | 0.82 | CYP2A6 (0.38) | NOTUMALDH1A1IDO1NPC1RAB9A | |
| SCHEMBL434140 | 0.82 | CYP1A2 (0.34) | NOTUMPDK2ALDH1A1IDO1KDM4E | |
| SCHEMBL432908 | 0.80 | PTGS1 (0.34) | NOTUMPDK2ALDH1A1CA1CA2 | |
| SCHEMBL8013535 | 0.77 | LMNA (0.36) | ALDH1A1MAPT | |
| SCHEMBL432706 | 0.76 | IDO1 (0.35) | ALDH1A1CA1CA2CA9IDO1 | |
| SCHEMBL6781593 | 0.76 | PTPN1 (0.37) | ALDH1A1CA9PTPN1 | |
| SCHEMBL8877797 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL16894699 | 0.75 | NPC1 (0.35) | NOTUMALDH1A1IDO1KDM4ENPC1 | |
| SCHEMBL434572 | 0.74 | NOTUM (0.35) | NOTUMALDH1A1IDO1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2850074-A1 | 1,3-DIARYL-SUBSTITUTED HETEROCYCLIC PESTICIDES | E. I. Du Pont de Nemours and Company (US) | 2015-03-25 | — | — | EP | disclosed |
| WO-2013173218-A1 | 1,3-DIARYL-SUBSTITUTED HETEROCYCLIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-11-21 | — | — | WO | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |