Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HEXA | P06865 | 2/20 | 0.46 |
| ▸ | HEXB | P07686 | 2/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351736 | 0.85 | GLS (0.62) | MAPTRAB9ASMN1; SMN2GLSMEN1 | |
| SCHEMBL56978 | 0.85 | GLS (0.62) | MAPTRAB9ASMN1; SMN2GLSMEN1 | |
| Hydrochloric Acid SCHEMBL10638625 | 0.83 | GLS (0.60) | MAPTRAB9ASMN1; SMN2GLSMEN1 | |
| SCHEMBL14560545 | 0.82 | DRD2 (0.50) | MAPTRAB9ASMN1; SMN2DRD2DRD3 | |
| SCHEMBL8879380 | 0.81 | HEXA (0.71) | MAPTRAB9ASMN1; SMN2HEXAHEXB | |
| SCHEMBL14468 | 0.79 | TDP1 (0.61) | MAPTRAB9ASMN1; SMN2GLSMEN1 | |
| SCHEMBL29459467 | 0.79 | TDP1 (0.61) | MAPTRAB9ASMN1; SMN2GLSMEN1 | |
| SCHEMBL14560547 | 0.79 | CDC25A (0.56) | DRD2DRD3ALDH1A1 | |
| SCHEMBL14560579 | 0.79 | DRD2 (0.48) | MAPTRAB9ASMN1; SMN2DRD2DRD3 | |
| SCHEMBL18744330 | 0.79 | DRD2 (0.48) | MAPTRAB9ASMN1; SMN2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046525-A1 | 5-ALKOXY-TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS 5-HT1D RECEPTOR AGONISTS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-12-11 | — | — | WO | disclosed |
| US-5654431-A | EXHIBIT SELECTIVITY TOWARDS 5-HYDROXYTRYPTAMINE RECEPTORS OF BRAIN CELLS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-08-05 | — | — | US | disclosed |