Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PYGL | P06737 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347961 | 0.85 | HDAC1 (0.47) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL2857498 | 0.84 | PYGL (0.43) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL14561875 | 0.83 | POLB (0.53) | CA1CA2CA9HDAC1POLB | |
| SCHEMBL7076639 | 0.83 | CA1 (0.51) | CA1CA2CA9HDAC1POLB | |
| SCHEMBL8076425 | 0.83 | HPGD (0.42) | POLBNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL18475963 | 0.83 | PYGL (0.44) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL31569318 | 0.81 | HDAC1 (0.47) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL10421172 | 0.81 | GPR35 (0.38) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL7689252 | 0.81 | HDAC1 (0.44) | CA1CA2CA9HDAC1HDAC6 | |
| SCHEMBL6202482 | 0.81 | CA1 (0.46) | CA1CA2CA9HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63310855-A | — | — | None | — | — | JP | disclosed |
| US-5631209-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5502027-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0415642-B1 | Glutarimides | ROHM & HAAS (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5393735-A | N-(halo-oxy-)phenyl substituted cyclic imides | ROHM AND HAAS COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0415641-B1 | Substituted glutaramic acids and derivatives | ROHM & HAAS (US) | 1994-01-19 | — | — | EP | disclosed |
| US-5238908-A | HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5084085-A | Plant growth regulators | FMC CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| EP-0415641-A1 | Substituted glutaramic acids and derivatives | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| EP-0415642-A1 | Glutarimides | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4885025-A | A PHENOXY-,-AMINO-,-ALKYLAMINO- OR -SULFIDO-SUBSTITUTED PHENYL ON THE NUMBER 1 RING NITROGEN | FMC CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| US-4816065-A | ARYLTETRAHYDROPHTHALIMIDES | FMC CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| JP-S63310855-A | 5-(1-BUTYN-3-YL)OXY-4-CHLORO-2-FLUOROACETANILIDE AND PRODUCTION THEREOF | SUMITOMO CHEM CO LTD | 1988-12-19 | — | — | JP | disclosed |