Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.60 |
| ▸ | HTR1A | P08908 | 10/20 | 0.56 |
| ▸ | DRD2 | P14416 | 7/20 | 0.56 |
| ▸ | HTR7 | P34969 | 6/20 | 0.56 |
| ▸ | HTR6 | P50406 | 6/20 | 0.56 |
| ▸ | HTR2A | P28223 | 5/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880695 | 0.91 | SLC6A4 (0.67) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL7259914 | 0.88 | ADRA1D (0.71) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL25758273 | 0.84 | SLC6A4 (0.66) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8876794 | 0.83 | SLC6A4 (0.64) | SLC6A4DRD2ADRA1D | |
| SCHEMBL8877539 | 0.83 | ADRA1D (0.79) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8879616 | 0.82 | SLC6A4 (0.55) | SLC6A4DRD2HTR7HTR2AADRA1D | |
| Hydrochloric Acid SCHEMBL7259917 | 0.80 | ADRA1D (0.51) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8820411 | 0.80 | SLC6A4 (0.60) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8876449 | 0.80 | SLC6A4 (0.60) | SLC6A4DRD2ADRA1D | |
| SCHEMBL8879141 | 0.80 | SLC6A4 (0.60) | SLC6A4DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670511-A | Indolepiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |