Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1185918 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPK1GAASMN1; SMN2TDP1 | |
| SCHEMBL8877353 | 0.85 | GAA (0.41) | ALDH1A1MAPK1GAASMN1; SMN2MEN1 | |
| SCHEMBL30958584 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPK1GAASMN1; SMN2TDP1 | |
| SCHEMBL7245515 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1GAASMN1; SMN2TDP1 | |
| SCHEMBL8876484 | 0.81 | GAA (0.42) | ALDH1A1GAASMN1; SMN2MEN1KMT2A | |
| Acetic Acid SCHEMBL8870017 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1GAASMN1; SMN2TDP1 | |
| SCHEMBL1187294 | 0.79 | PTPN1 (0.38) | ALDH1A1MAPK1SMN1; SMN2TDP1CRBN | |
| SCHEMBL30194898 | 0.79 | PTPN1 (0.38) | ALDH1A1MAPK1SMN1; SMN2TDP1CRBN | |
| SCHEMBL1994444 | 0.79 | MAPT (0.43) | ALDH1A1GAASMN1; SMN2TDP1MAPT | |
| SCHEMBL29162697 | 0.78 | CES2 (0.48) | ALDH1A1MAPK1GAASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672708-A | Process for the preparation of N-arylaminoacrylic acid derivatives and the use of N-arylaminoacrylic acid derivatives thus prepared for the preparation of 4-quinolone-3-carboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |
| EP-0239992-B1 | PROCESS FOR THE PREPARATION OF 2,3,4,5-TETRAFLUOROBENZOYL ACETATES | WARNER-LAMBERT COMPANY (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4772706-A | Process for quinoline-3-carboxylic acid antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0239992-A1 | Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates | WARNER-LAMBERT COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |
| EP-0239992-A1 | Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates | WARNER-LAMBERT COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |
| EP-0236673-A2 | Process for quinoline-3-carboxylic acid antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4689423-A | Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates | WARNER-LAMBERT COMPANY (US) | 1987-08-25 | — | — | US | disclosed |
| US-4689423-A | Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates | WARNER-LAMBERT COMPANY (US) | 1987-08-25 | — | — | US | disclosed |