Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878202 | 0.85 | KDM4E (0.44) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL8878155 | 0.79 | KDM4E (0.47) | ALDH1A1DRD3SMN1; SMN2KDM4EHPGD | |
| SCHEMBL8732186 | 0.79 | KDM4E (0.45) | ALDH1A1HTR4KDM4EHPGDHSD17B10 | |
| SCHEMBL8735561 | 0.77 | KDM4E (0.52) | ALDH1A1DRD3SMN1; SMN2KDM4EHPGD | |
| SCHEMBL8880183 | 0.75 | KCNH2 (0.57) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL8732413 | 0.74 | KCNH2 (0.56) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL8880495 | 0.72 | HTR4 (0.40) | ALDH1A1HTR4DRD3KDM4EHPGD | |
| SCHEMBL8057309 | 0.71 | KDM4E (0.46) | ALDH1A1DRD2DRD3SMN1; SMN2KDM4E | |
| SCHEMBL8877142 | 0.70 | KDM4E (0.39) | ALDH1A1HTR4SMN1; SMN2KDM4EHPGD | |
| SCHEMBL24177747 | 0.70 | ALDH1A1 (0.97) | ALDH1A1SMN1; SMN2KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | claimed |
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | claimed |
| US-5688791-A | COMPOUNDS FOR TREATMENNT OF VIRAL DISEASES SUCH AS AIDS | UBE INDUSTRIES, LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |