SCHEMBL8878503

SCHEMBL8878503

CC(C)CS(=O)(=O)c1cc(N2C(=O)CC(C(F)(F)F)CC2=O)c(F)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPOX P50336 2/20 0.32
KCNQ3 O43525 1/20 0.31
KCNQ2 O43526 1/20 0.31
KCNE1 P15382 1/20 0.31
KCNQ1 P51787 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8877805 0.76 PPOX (0.38) PPOX
SCHEMBL8877808 0.75 PPOX (0.40) PPOX
SCHEMBL9843822 0.75 PSIP1 (0.35) PPOX
SCHEMBL8879045 0.74 PPOX (0.35) PPOX
SCHEMBL8878819 0.72 TSHR (0.36) PPOX
SCHEMBL9211922 0.72 PPOX (0.36) PPOX
SCHEMBL8879502 0.71 ALDH1A1 (0.44) PPOX
SCHEMBL8876677 0.71 EPHX2 (0.36) PPOX
SCHEMBL8879992 0.71 HPGD (0.33) PPOX
SCHEMBL8878270 0.70 DPP4 (0.38) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631209-A ALGICIDES ROHM AND HAAS COMPANY (US) 1997-05-20 US disclosed
US-5502027-A ALGICIDES ROHM AND HAAS COMPANY (US) 1996-03-26 US disclosed
EP-0415642-B1 Glutarimides ROHM & HAAS (US) 1995-12-06 EP disclosed
US-5393735-A N-(halo-oxy-)phenyl substituted cyclic imides ROHM AND HAAS COMPANY (US) 1995-02-28 US disclosed
EP-0415642-A1 Glutarimides ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed