SCHEMBL8878622

SCHEMBL8878622

CC(CO)c1ccc2ccccc2c1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
HPGD P15428 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 2/20 0.47
GLA P06280 2/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
ACE2 Q9BYF1 2/20 0.46
METAP2 P50579 2/20 0.44
METAP1 P53582 1/20 0.44
WDR5 P61964 1/20 0.41
LDHA P00338 1/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
CDC25B P30305 1/20 0.39
AKR1B1 P15121 1/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14151165 0.88 MEN1 (0.47) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL248045 0.83 KDM4E (0.53) ALDH1A1HPGDMEN1KMT2AKDM4E
Propylene Glycol SCHEMBL27835765 0.77 WDR5 (0.51) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL27986188 0.75 ALDH1A1 (0.44) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL3412393 0.74 CYP1A2 (0.50) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL8877614 0.73 TSHR (0.41) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL5656111 0.72 HPRT1 (0.48) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL10797196 0.72 HSD17B10 (0.47) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL897607 0.71 KDM4E (0.55) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL224932 0.71 HPGD (0.59) ALDH1A1HPGDMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639922-A CONTACTING AROMATIC PRIMARY AND TERTIARY HYDROPEROXIDES MIXTURE OBTAINED BY OXIDATION OF ALKYLAROMATIC COMPOUNDS WITH AN ALKALI OR ALKALINE ORGANIC AROMATIC CARBOXYLIC ACID SALT, DECOMPOSING WITH ACID CATALYST FORMING ALKYL PHENOLS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-17 US disclosed