Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 12/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718310 | 0.83 | CHRM3 (0.54) | CHRM3LMNACYP2D6KMT2ACHRM2 | |
| Maleic Acid SCHEMBL10719202 | 0.78 | CHRM3 (0.49) | CHRM3LMNACYP2D6KMT2ACHRM2 | |
| SCHEMBL20556104 | 0.77 | MEN1 (0.38) | CHRM3LMNACYP2D6MEN1HRH1 | |
| SCHEMBL4756753 | 0.77 | CHRM3 (0.50) | CHRM3LMNACYP2D6KMT2ACHRM2 | |
| SCHEMBL8878260 | 0.76 | CHRM3 (0.56) | CHRM3 | |
| SCHEMBL4758054 | 0.76 | CHRM3 (0.49) | CHRM3LMNACYP2D6KMT2ACHRM2 | |
| SCHEMBL10516709 | 0.76 | CYP2D6 (0.56) | CHRM3LMNACYP2D6MEN1HRH1 | |
| SCHEMBL10467517 | 0.75 | CHRM3 (0.65) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2341663 | 0.74 | KCNH2 (0.56) | CHRM3LMNACYP2D6MEN1KMT2A | |
| SCHEMBL23777916 | 0.74 | CHRM3 (0.97) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607950-A | IRRITABLE BOWEL SYNDROME | PFIZER INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0508988-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-03-02 | — | — | EP | disclosed |
| WO-1991010647-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |