Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CETP | P11597 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467517 | 0.77 | CHRM3 (0.65) | TSHRCHRM3CHRM2CHRM1SMN1; SMN2 | |
| SCHEMBL8878800 | 0.74 | CHRM3 (0.59) | KCNH2CHRM3CHRM2CHRM1CYP2D6 | |
| Vamicamide SCHEMBL331820 | 0.73 | KCNH2 (0.65) | KCNH2BLMSLC22A2SLC22A1PGR | |
| Vamicamide SCHEMBL9393264 | 0.73 | KCNH2 (0.65) | KCNH2BLMSLC22A2SLC22A1PGR | |
| Vamicamide SCHEMBL30700593 | 0.73 | KCNH2 (0.65) | KCNH2BLMSLC22A2SLC22A1PGR | |
| Disopyramide SCHEMBL23931452 | 0.72 | KCNH2 (1.00) | KCNH2BLMSLC22A2SLC22A1PGR | |
| (S)-Disopyramide SCHEMBL41811 | 0.72 | KCNH2 (1.00) | KCNH2BLMSLC22A2SLC22A1PGR | |
| Disopyramide SCHEMBL16153 | 0.72 | KCNH2 (1.00) | KCNH2BLMSLC22A2SLC22A1PGR | |
| Vamicamide SCHEMBL9393357 | 0.72 | KCNH2 (0.64) | KCNH2BLMSLC22A2SLC22A1PGR | |
| Vamicamide SCHEMBL4603765 | 0.72 | KCNH2 (0.64) | KCNH2BLMSLC22A2SLC22A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358750-A2 | COMPOSITIONS AND METHODS FOR MODULATING CELL-CELL FUSION VIA INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | Boehringer Ingelheim International GmbH (DE) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010053584-A2 | COMPOSITIONS AND METHODS FOR MODULATING CELL-CELL FUSION VIA INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-14 | — | — | WO | disclosed |