SCHEMBL887883

SCHEMBL887883

O=c1ccc(I)c[nH]1.O=c1cccc[nH]1

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FKBP5 Q13451 1/20 0.64
ALDH1A1 P00352 2/20 0.39
NOTUM Q6P988 1/20 0.34
PKM P14618 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL629361 0.85
SCHEMBL9596 0.80
SCHEMBL27324502 0.80 FKBP5 (1.00) FKBP5ALDH1A1NOTUML3MBTL1KDM4E
SCHEMBL8004964 0.78
SCHEMBL9813332 0.78
SCHEMBL25414048 0.78
SCHEMBL1149107 0.78
Methane SCHEMBL22588025 0.78
Water SCHEMBL14333714 0.78
SCHEMBL98973 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3401407-A1 NUCLEIC ACID PROBE, METHOD FOR DESIGNING NUCLEIC ACID PROBE, AND METHOD FOR DETECTING TARGET SEQUENCE Kabushiki Kaisha Dnaform (JP) 2018-11-14 EP claimed
US-10066264-B2 Method for analyzing target nucleic acid, kit, and analyzer KABUSHIKI KAISHA DNAFORM (JP) 2018-09-04 US claimed
EP-2873731-B1 NUCLEIC ACID PROBE, METHOD FOR DESIGNING NUCLEIC ACID PROBE, AND METHOD FOR DETECTING TARGET SEQUENCE DNAFORM KK (JP) 2018-08-29 EP claimed
EP-2891714-B1 METHOD FOR ANALYZING TARGET NUCLEIC ACID, KIT, AND ANALYZER DNAFORM KK (JP) 2018-07-11 EP claimed
US-9862989-B2 Nucleic acid probe, method for designing nucleic acid probe, and method for detecting target sequence KABUSHIKI KAISHA DNAFORM (JP) 2018-01-09 US claimed
US-20150203902-A1 NUCLEIC ACID PROBE, METHOD FOR DESIGNING NUCLEIC ACID PROBE, AND METHOD FOR DETECTING TARGET SEQUENCE KABUSHIKI KAISHA DNAFORM (JP) 2015-07-23 US claimed
EP-2891714-A1 METHOD FOR ANALYZING TARGET NUCLEIC ACID, KIT, AND ANALYZER Kabushiki Kaisha Dnaform (JP) 2015-07-08 EP claimed
US-20150152496-A1 METHOD FOR ANALYZING TARGET NUCLEIC ACID, KIT, AND ANALYZER KABUSHIKI KAISHA DNAFORM (JP) 2015-06-04 US claimed
EP-2873731-A1 NUCLEIC ACID PROBE, METHOD FOR DESIGNING NUCLEIC ACID PROBE, AND METHOD FOR DETECTING TARGET SEQUENCE Kabushiki Kaisha Dnaform (JP) 2015-05-20 EP claimed
US-10760116-B2 Analysis kit, analyzer, and methods for analyzing template nucleic acid or target substance KABUSHIKI KAISHA DNAFORM (JP) 2020-09-01 US disclosed
EP-3339447-B1 METHOD FOR ANALYZING TEMPLATE NUCLEIC ACID, METHOD FOR ANALYZING TARGET SUBSTANCE, ANALYSIS KIT FOR TEMPLATE NUCLEIC ACID OR TARGET SUBSTANCE, AND ANALYZER FOR TEMPLATE NUCLEIC ACID OR TARGET SUBSTANCE DNAFORM KK (JP) 2020-07-29 EP disclosed
EP-3401407-B1 NUCLEIC ACID PROBE, METHOD FOR DESIGNING NUCLEIC ACID PROBE, AND METHOD FOR DETECTING TARGET SEQUENCE DNAFORM KK (JP) 2020-04-22 EP disclosed
US-10428371-B2 Fluorescent labeled single-stranded nucleic acid and use thereof KABUSHIKI KAISHA DNAFORM (JP) 2019-10-01 US disclosed
US-20190032108-A1 METHOD FOR ANALYZING TEMPLATE NUCLEIC ACID, METHOD FOR ANALYZING TARGET SUBSTANCE, ANALYSIS KIT FOR TEMPLATE NUCLEIC ACID OR TARGET SUBSTANCE, AND ANALYZER FOR TEMPLATE NUCLEIC ACID OR TARGET SUBSTANCE RIKEN (JP) 2019-01-31 US disclosed
US-20150152496-A1 METHOD FOR ANALYZING TARGET NUCLEIC ACID, KIT, AND ANALYZER KABUSHIKI KAISHA DNAFORM (JP) 2015-06-04 US disclosed
EP-2873731-A1 NUCLEIC ACID PROBE, METHOD FOR DESIGNING NUCLEIC ACID PROBE, AND METHOD FOR DETECTING TARGET SEQUENCE Kabushiki Kaisha Dnaform (JP) 2015-05-20 EP disclosed
EP-1970453-B1 Primer, primer set, and nucleic acid amplification method and mutation detection method using the same RIKEN (JP) 2012-08-01 EP disclosed
US-8067162-B2 Replication; hybridization; kits RIKEN (JP) 2011-11-29 US disclosed
US-20080227104-A1 Replication; hybridization; kits RIKEN (JP) 2008-09-18 US disclosed
EP-1970453-A2 Primer, primer set, and nucleic acid amplification method and mutation detection method using the same Riken (JP) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227104-A1 Replication; hybridization; kits PCNA, POLL, RNGTT FKBP5 2130/4885ALDH1A1 4584/4885NOTUM 3074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.