Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13847093 | 0.80 | FGFR1 (0.31) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL13379601 | 0.76 | ALDH1A1 (0.48) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL12985338 | 0.76 | FGFR1 (0.57) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL13475404 | 0.76 | MEN1 (0.36) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL13060279 | 0.76 | BLM (0.54) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL13071348 | 0.75 | BLM (0.47) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL8845705 | 0.74 | PNP (0.44) | BLM | |
| SCHEMBL13475348 | 0.68 | ADK (0.41) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL9666275 | 0.67 | BLM (0.55) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL543442 | 0.67 | FGFR1 (0.62) | MEN1ALDH1A1LMNACYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7883869-B2 | for sequencing single-stranded DNA by employing a nanopore and modified nucleotides | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-02-08 | — | — | US | disclosed |
| US-20100092952-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-04-15 | — | — | US | disclosed |