Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 12/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23584555 | 0.87 | ADK (0.54) | ADKSLC29A1ALDH1A1LMNAALB | |
| SCHEMBL23641741 | 0.87 | ADK (0.43) | ADKSLC29A1ALDH1A1LMNAALB | |
| SCHEMBL13065176 | 0.86 | ADK (0.53) | ADKSLC29A1ALDH1A1LMNAALB | |
| SCHEMBL12993150 | 0.86 | ADK (0.53) | ADKSLC29A1ALDH1A1LMNAALB | |
| SCHEMBL19343834 | 0.86 | ADK (0.52) | ADKSLC29A1ALDH1A1LMNAALB | |
| SCHEMBL19647645 | 0.86 | ADK (0.42) | ADKSLC29A1ALDH1A1LMNAALB | |
| SCHEMBL23584606 | 0.86 | ADK (0.42) | ADKSLC29A1ALDH1A1LMNAALB | |
| SCHEMBL23892559 | 0.86 | ALDH1A1 (0.43) | ADKSLC29A1ALDH1A1LMNAALB | |
| SCHEMBL13349028 | 0.86 | ADK (0.53) | ADKSLC29A1ALDH1A1LMNAALB | |
| SCHEMBL23641680 | 0.85 | ADK (0.60) | ADKSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307565-B1 | REVERSIBLE NUCLEOSIDES AND NUCLEOTIDES TERMINATORS AND THEIR USE IN DNA SEQUENCING | LASERGEN INC (US) | 2017-11-29 | — | — | EP | disclosed |
| US-8148503-B2 | Nucleotides and nucleosides and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-7883869-B2 | for sequencing single-stranded DNA by employing a nanopore and modified nucleotides | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-02-08 | — | — | US | disclosed |
| US-20100092952-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-04-15 | — | — | US | disclosed |