SCHEMBL19647645

SCHEMBL19647645

OCc1cn([C@H]2CC[C@@H](CO)O2)c2ncnc(Cl)c12

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADK P55263 10/20 0.42
SLC29A1 Q99808 1/20 0.42
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
ALB P02768 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP1A2 P05177 1/20 0.36
ABL1 P00519 1/20 0.35
RIN1 Q13671 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23584555 0.87 ADK (0.54) ADKSLC29A1ALDH1A1LMNAALB
SCHEMBL23892559 0.86 ALDH1A1 (0.43) ADKSLC29A1ALDH1A1LMNAALB
SCHEMBL19343834 0.86 ADK (0.52) ADKSLC29A1ALDH1A1LMNAALB
SCHEMBL23584606 0.86 ADK (0.42) ADKSLC29A1ALDH1A1LMNAALB
SCHEMBL887898 0.86 ADK (0.58) ADKSLC29A1ALDH1A1LMNAALB
SCHEMBL20938334 0.79 METTL3 (0.43) ADKALDH1A1LMNAALBMAPK1
SCHEMBL24600957 0.77 ALDH1A1 (0.60) ALDH1A1LMNAALBMAPK1CYP1A2
SCHEMBL2035453 0.77 ALDH1A1 (0.60) ALDH1A1LMNAALBMAPK1CYP1A2
SCHEMBL2035452 0.77 ALDH1A1 (0.60) ALDH1A1LMNAALBMAPK1CYP1A2
SCHEMBL18572595 0.76 ALDH1A1 (0.42) ALDH1A1LMNAALBMAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2307565-B1 REVERSIBLE NUCLEOSIDES AND NUCLEOTIDES TERMINATORS AND THEIR USE IN DNA SEQUENCING LASERGEN INC (US) 2017-11-29 EP disclosed