Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.54 |
| ▸ | MET | P08581 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447188 | 0.89 | ALDH1A1 (0.60) | EPHX2KDM4EGAAFDPS | |
| Methyl Sinapate SCHEMBL2517008 | 0.87 | CYP1A2 (0.74) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL6072489 | 0.87 | PKM (0.57) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL30812355 | 0.87 | PKM (0.57) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| Methyl Sinapate SCHEMBL9908304 | 0.87 | CYP1A2 (0.74) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| Methyl Cis-Ferulate SCHEMBL29374619 | 0.83 | EPHX2 (0.78) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| Methyl Cis-Ferulate SCHEMBL887914 | 0.83 | EPHX2 (0.78) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| Methyl Cis-Ferulate SCHEMBL30298752 | 0.83 | EPHX2 (0.78) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL7158939 | 0.81 | EPHX2 (0.69) | PTGS1PKMPTGS2CYP1A2CYP3A4 | |
| SCHEMBL19202508 | 0.80 | EPHX2 (0.63) | PTGS1PKMPTGS2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058513-B2 | Polypeptides having feruloyl esterase activity and polynucleotides encoding same | NOVOZYMES, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-8034995-B2 | Polypeptides having feruloyl esterase activity and polynucleotides encoding same | NOVOZYMES A/S (DK) | 2011-10-11 | — | — | US | disclosed |
| EP-2356136-A1 | POLYPEPTIDES HAVING FERULOYL ESTERASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | Novozymes Inc. (US) | 2011-08-17 | — | — | EP | disclosed |
| US-20090151026-A1 | Polypeptides having feruloyl esterase activity and polynucleotides encoding same | NOVOZYMES A/S (DK) | 2009-06-11 | — | — | US | disclosed |