Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288862 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11672499 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL5251134 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11672493 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9816485 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6448104 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL2956122 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL1207736 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL531156 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL5251136 | 0.97 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145499-A1 | METHODS FOR INDEXING SAMPLES AND SEQUENCING MULTIPLE POLYNUCLEOTIDE TEMPLATES | ILLUMINA CAMBRIDGE LIMITED (US) | 2017-05-25 | — | — | US | disclosed |
| US-20120316072-A1 | Methods for indexing samples and sequencing multiple polynucleotide templates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-12-13 | — | — | US | disclosed |
| US-20120309634-A1 | METHOD FOR PAIRWISE SEQUENCING OF TARGET POLYNUCLEOTIDES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-12-06 | — | — | US | disclosed |
| US-20120208194-A1 | Preparation of Templates for Nucleic Acid Sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-08-16 | — | — | US | disclosed |
| US-8236505-B2 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-08-07 | — | — | US | disclosed |
| US-20120094848-A1 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| US-8105784-B2 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-01-31 | — | — | US | disclosed |
| US-8053192-B2 | Methods for indexing samples and sequencing multiple polynucleotide templates | ILLUMINA CAMBRIDGE LTD. (GB) | 2011-11-08 | — | — | US | disclosed |
| US-20110223601-A1 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2011-09-15 | — | — | US | disclosed |
| US-7960120-B2 | Method for pair-wise sequencing a plurality of double stranded target polynucleotides | ILLUMINA CAMBRIDGE LTD. (GB) | 2011-06-14 | — | — | US | disclosed |
| US-20110014657-A1 | Method for sequencing a polynucleotide template | ILLUMINA CAMBRIDGE LTD. | 2011-01-20 | — | — | US | disclosed |
| US-7754429-B2 | Method for pair-wise sequencing a plurity of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-07-13 | — | — | US | disclosed |
| US-20090233802-A1 | Methods for indexing samples and sequencing multiple polynucleotide templates | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-17 | — | — | US | disclosed |
| US-20090118128-A1 | Preparation of templates for nucleic acid sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2009-05-07 | — | — | US | disclosed |
| US-20090088327-A1 | Method for sequencing a polynucleotide template | SOLEXA LIMITED (GB) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118128-A1 | Preparation of templates for nucleic acid sequencing | RNGTT, POLRMT, POLM | LMNA 211/4885HSD17B10 2198/4885ALDH1A1 3780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.