Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.66 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 3/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282972 | 0.85 | ITGB3 (0.86) | ITGB3ITGA2BF10KMT2A | |
| SCHEMBL8881734 | 0.82 | NMBR (0.58) | FPR2MEN1KMT2ATACR1 | |
| SCHEMBL7276540 | 0.82 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL7283177 | 0.82 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL8689594 | 0.81 | DPP4 (0.56) | MEN1KMT2A | |
| SCHEMBL8689586 | 0.81 | DPP4 (0.56) | MEN1KMT2A | |
| SCHEMBL8379088 | 0.81 | ITGB3 (0.78) | ITGB3ITGA2B | |
| SCHEMBL7294041 | 0.81 | ITGB3 (0.78) | ITGB3ITGA2B | |
| SCHEMBL8882836 | 0.80 | ITGB3 (0.75) | ITGB3ITGA2B | |
| Lamifiban SCHEMBL4683 | 0.80 | ITGB3 (1.00) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658928-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS,WOUND HEALING AGENTS, OSTEOPOROSIS | HOFFMANN-LA ROCHE INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5545658-A | FOR TREATMENT OR PROPHYLAXIS OF ILLNESSES WHICH ARE CAUSED BY THE BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELETS AND BY BLOOD PLATELET AGGREGATION AND CELL-CELL ADHESION | HOFFMAN-LA ROCHE INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5378712-A | Antithrombosis | Hoffmann-La Roche Inc (US) | 1995-01-03 | — | — | US | disclosed |