Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878576 | 0.93 | SLC6A4 (0.55) | SLC6A4ADRA1DHTR1A | |
| SCHEMBL8876433 | 0.87 | SLC6A4 (0.61) | SLC6A4ADRA1D | |
| SCHEMBL8877318 | 0.86 | SLC6A4 (0.57) | SLC6A4ADRA1D | |
| SCHEMBL5385643 | 0.85 | HTR4 (0.48) | SLC6A4ADRA1D | |
| SCHEMBL8876262 | 0.84 | SLC6A4 (0.57) | SLC6A4ADRA1D | |
| SCHEMBL5392667 | 0.83 | SLC6A4 (0.52) | SLC6A4ADRA1D | |
| SCHEMBL5380517 | 0.82 | HTR1F (0.48) | SLC6A4ADRA1DHTR1A | |
| SCHEMBL5705230 | 0.81 | SLC6A4 (0.90) | SLC6A4ADRA1D | |
| SCHEMBL9231794 | 0.81 | HTR2A (0.57) | SLC6A4ADRA1DHTR1A | |
| SCHEMBL8554029 | 0.80 | HTR1A (0.70) | SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670511-A | Indolepiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |