Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879407 | 0.88 | DPP4 (0.53) | ITGB3ITGA2BOPRD1DPP4F2 | |
| SCHEMBL8879394 | 0.88 | DPP4 (0.53) | ITGB3ITGA2BOPRD1DPP4F2 | |
| SCHEMBL7797514 | 0.85 | ITGB3 (0.64) | ITGB3ITGA2BOPRD1DPP4F2 | |
| SCHEMBL7797516 | 0.85 | ITGB3 (0.64) | ITGB3ITGA2BOPRD1DPP4F2 | |
| SCHEMBL8690139 | 0.82 | DPP4 (0.42) | OPRD1DPP4FAPDPP8DPP9 | |
| SCHEMBL8881449 | 0.82 | HRH2 (0.49) | ITGB3ITGA2BHRH2HRH1 | |
| SCHEMBL8690140 | 0.81 | OPRD1 (0.45) | OPRD1DPP4FAPDPP8DPP9 | |
| SCHEMBL8880911 | 0.81 | ITGB3 (0.78) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL8480731 | 0.78 | DPP4 (0.49) | ITGB3ITGA2BOPRD1DPP4F2 | |
| SCHEMBL8396803 | 0.77 | ITGB3 (0.51) | ITGB3ITGA2BPOLBHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658928-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS,WOUND HEALING AGENTS, OSTEOPOROSIS | HOFFMANN-LA ROCHE INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5545658-A | FOR TREATMENT OR PROPHYLAXIS OF ILLNESSES WHICH ARE CAUSED BY THE BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELETS AND BY BLOOD PLATELET AGGREGATION AND CELL-CELL ADHESION | HOFFMAN-LA ROCHE INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5378712-A | Antithrombosis | Hoffmann-La Roche Inc (US) | 1995-01-03 | — | — | US | disclosed |