Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670282 | 0.91 | LMNA (0.53) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL16664042 | 0.87 | CA12 (0.56) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL10965456 | 0.84 | LOXL2 (0.59) | CYP1A2CYP3A4CA1CA2CA12 | |
| SCHEMBL20715467 | 0.84 | LMNA (0.64) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL12199135 | 0.83 | CA1 (0.68) | LMNACYP1A2CYP3A4MAOACA1 | |
| Hydrochloric Acid SCHEMBL6364657 | 0.83 | LOXL2 (0.57) | CYP1A2CYP3A4CA1CA2CA12 | |
| SCHEMBL21058230 | 0.82 | CYP4F2 (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13153523 | 0.81 | CA12 (0.53) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL5734417 | 0.80 | LMNA (0.68) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL571227 | 0.80 | CA1 (0.63) | LMNACYP1A2CYP3A4MAOACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | claimed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | claimed |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | disclosed |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | disclosed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | disclosed |
| US-5672713-A | Herbicidal and fungicidal substituted triazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |
| US-5516749-A | Herbicidal and fungicidal substituted triazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| EP-0586418-A1 | SUBSTITUTED TRIAZOLINONES | BAYER AG (DE) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020663-A1 | SUBSTITUTED TRIAZOLINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-26 | — | — | WO | disclosed |
| EP-0505819-A1 | Substituted triazolinones | BAYER AG (DE) | 1992-09-30 | — | — | EP | disclosed |
| EP-0502307-A2 | Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones | BAYER AG (DE) | 1992-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | CHKB, HRH3, PNMT | LMNA 3235/4885CYP1A2 2448/4885CYP3A4 1925/4885 |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | CHKB, HRH3, PNMT | LMNA 3249/4885CYP1A2 2410/4885CYP3A4 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.