Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049364 | 0.79 | SLC6A4 (0.47) | HTR2CADRB2SLC6A4IMPDH2IMPDH1 | |
| SCHEMBL4670703 | 0.78 | HTR2C (0.58) | HTR2CADRB2SLC6A4APPHTR6 | |
| SCHEMBL5387687 | 0.78 | SLC6A4 (0.59) | HTR2CADRB2SLC6A4APPHTR6 | |
| SCHEMBL26965710 | 0.78 | HTR2C (0.58) | HTR2CADRB2SLC6A4APP | |
| SCHEMBL8876262 | 0.76 | SLC6A4 (0.57) | SLC6A4 | |
| SCHEMBL1513147 | 0.75 | HTR2C (0.55) | HTR2CADRB2SLC6A4IKBKB | |
| SCHEMBL8554103 | 0.74 | HTR2C (0.60) | HTR2CADRB2SLC6A4HTR6 | |
| SCHEMBL8875495 | 0.74 | HTR2C (0.59) | HTR2CADRB2SLC6A4APPHTR6 | |
| Oxalic Acid SCHEMBL7870865 | 0.74 | SLC6A4 (0.47) | SLC6A4HTR6NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL4739383 | 0.73 | HTR2C (0.56) | HTR2CADRB2SLC6A4GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670511-A | Indolepiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-09-23 | — | — | US | disclosed |
| CN-1133840-A | Indolepiperidine derivatives | MERCK PATENT GMBH (DE) | 1996-10-23 | — | — | CN | disclosed |
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |