SCHEMBL887984

SCHEMBL887984

OC[C@H]1O[C@H](OCCS)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 3/20 0.62
LGALS3 P17931 3/20 0.62
LGALS4 P56470 3/20 0.62
GAA P10253 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.46
TYR P14679 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16129417 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18746352 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL10070674 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18746353 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18387240 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18383020 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL10298049 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL16900305 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18387241 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL13895786 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220047718-A1 Nanoparticle-Based Therapy of Inflammatory Disorders MIDATECH LTD (GB) 2022-02-17 US claimed
EP-3893938-A1 ANTIFOLATE-CARRYING NANOPARTICLES AND THEIR USE IN MEDICINE Midatech Ltd (GB) 2021-10-20 EP claimed
EP-3893939-A1 NANOPARTICLE-BASED THERAPY OF INFLAMMATORY DISORDERS Midatech Ltd (GB) 2021-10-20 EP claimed
CN-113423433-A Nanoparticles carrying antifolates and their use in medicine MIDA科技有限公司 2021-09-21 CN claimed
WO-2020120787-A1 NANOPARTICLE-BASED THERAPY OF INFLAMMATORY DISORDERS MIDATECH LTD (GB) 2020-06-18 WO claimed
WO-2020120785-A1 ANTIFOLATE-CARRYING NANOPARTICLES AND THEIR USE IN MEDICINE MIDATECH LTD (GB) 2020-06-18 WO claimed
US-20190039039-A1 NANOPARTICLE PRODUCTION MIDATECH LTD (GB) 2019-02-07 US claimed
EP-2579898-B1 PEPTIDE-CARRYING NANOPARTICLES MIDATECH LTD (GB) 2019-01-09 EP claimed
EP-3419748-A1 NANOPARTICLE PRODUCTION Midatech Ltd (GB) 2019-01-02 EP claimed
EP-2717858-B1 COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME AQUESTIVE THERAPEUTICS INC (US) 2018-08-08 EP claimed
US-20140220135-A1 PERMEATION ENHANCED ACTIVE-CARRYING NANOPARTICLES MIDATECH LTD (GB) 2014-08-07 US claimed
US-8790704-B2 Combination peptide-nanoparticles and delivery systems incorporating same MONOSOL RX, LLC (US) 2014-07-29 US claimed
EP-2717858-A1 COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME MonoSol Rx, LLC (US) 2014-04-16 EP claimed
US-8568781-B2 Peptide-carrying nanoparticles MIDATECH LIMITED (GB) 2013-10-29 US claimed
EP-2579844-A1 NANOPARTICLE FILM DELIVERY SYSTEMS Schobel, Alexander M. (US) 2013-04-17 EP claimed
EP-2579898-A1 PEPTIDE-CARRYING NANOPARTICLES Midatech Ltd. (GB) 2013-04-17 EP claimed
WO-2012170828-A1 COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME MONOSOL RX, LLC (US) 2012-12-13 WO claimed
US-20120301535-A1 COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME AQUESTIVE THERAPEUTICS, INC. 2012-11-29 US claimed
US-20120171291-A1 PEPTIDE-CARRYING NANOPARTICLES MIDATECH PHARMA PLC (GB) 2012-07-05 US claimed
US-20120009260-A1 NANOPARTICLE FILM DELIVERY SYSTEMS AQUESTIVE THERAPEUTICS, INC. 2012-01-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120171291-A1 PEPTIDE-CARRYING NANOPARTICLES CALCA, LNPEP, CLTA LGALS8 160/4885LGALS3 99/4885LGALS4 134/4885
US-20190039039-A1 NANOPARTICLE PRODUCTION CLTA, CORO1A, NAPA LGALS8 1226/4885LGALS3 307/4885LGALS4 335/4885
US-20120009260-A1 NANOPARTICLE FILM DELIVERY SYSTEMS CD63, DSTN, EPCAM LGALS8 878/4885LGALS3 369/4885LGALS4 1202/4885
US-20120301535-A1 COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME CALCA, LNPEP, IAPP LGALS8 260/4885LGALS3 156/4885LGALS4 196/4885
US-20220047718-A1 Nanoparticle-Based Therapy of Inflammatory Disorders MTX1, LANCL1, CD44 LGALS8 273/4885LGALS3 60/4885LGALS4 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.