Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042914 | 0.87 | CTSK (0.42) | CTSKSLC1A3SLC1A2CACNA2D1CACNB3 | |
| SCHEMBL7053522 | 0.81 | SLC1A3 (0.38) | CTSKSLC1A3SLC1A2SLC1A1CA1 | |
| SCHEMBL11706532 | 0.79 | CTSK (0.38) | CTSKCACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL24465735 | 0.76 | FAAH (0.37) | SLC1A3SLC1A2SLC1A1CA1MMP1 | |
| SCHEMBL6665926 | 0.75 | CYP19A1 (0.40) | CTSKSLC1A3SLC1A2CACNA2D1CACNB3 | |
| SCHEMBL16047304 | 0.73 | SLC1A3 (0.33) | CTSKSLC1A3SLC1A2SLC1A1CACNA2D1 | |
| SCHEMBL15992968 | 0.72 | HCAR2 (0.53) | CTSKSLC1A3SLC1A2SLC1A1CACNA2D1 | |
| SCHEMBL10624574 | 0.71 | RNPEP (0.34) | CTSKSLC1A3SLC1A2CACNA2D1CACNB3 | |
| SCHEMBL16047974 | 0.71 | CTSK (0.33) | CTSKSLC1A3SLC1A2SLC1A1CA1 | |
| SCHEMBL16047761 | 0.71 | CA1 (0.34) | CTSKSLC1A3SLC1A2SLC1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684015-A | ANGIOTENSIN ANTAGONIST AS HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-11-04 | — | — | US | disclosed |