Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22127608 | 0.82 | GABRR1 (0.46) | FAAHCNR1CNR2MMP1MMP2 | |
| SCHEMBL7360956 | 0.81 | — | — | |
| SCHEMBL14991062 | 0.80 | CA1 (0.39) | FAAHCA1CNR1CNR2SLC1A3 | |
| SCHEMBL6665926 | 0.80 | CYP19A1 (0.40) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL14590461 | 0.78 | TSHR (0.52) | FAAHCA1CNR1CNR2SLC1A3 | |
| SCHEMBL11391992 | 0.77 | CHRNB2 (0.34) | FAAH | |
| SCHEMBL11662694 | 0.77 | FAAH (0.50) | FAAHCA1CNR1CNR2LMNA | |
| SCHEMBL10608689 | 0.76 | FAAH (0.57) | FAAHCA1CNR1CNR2LMNA | |
| SCHEMBL8880146 | 0.76 | CTSK (0.38) | CA1MMP1MMP2MMP3MMP9 | |
| SCHEMBL22127579 | 0.76 | CA2 (0.47) | FAAHCA1CNR1CNR2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681884-B1 | RAD51 INHIBITORS | CYTEIR THERAPEUTICS INC (US) | 2022-06-01 | — | — | EP | disclosed |