SCHEMBL888019

SCHEMBL888019

O=[C]c1ccc(Oc2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.57
TSHR P16473 1/20 0.57
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
MAOA P21397 1/20 0.50
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
GSTP1 P09211 1/20 0.47
SOS1 Q07889 1/20 0.47
CA9 Q16790 1/20 0.47
PARP10 Q53GL7 1/20 0.47
PLA2G2A P14555 1/20 0.47
SRD5A2 P31213 1/20 0.45
FFAR1 O14842 1/20 0.45
MGLL Q99685 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL97638 1.00 LTA4H (0.57) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL9422169 0.90 PARP15 (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL9654773 0.90 PARP15 (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3085615 0.89 FFAR1 (0.52) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL21925450 0.87 SRD5A2 (0.68) PARP10SRD5A2
SCHEMBL9422165 0.86 ALDH1A1 (0.54) LTA4HTSHRGSTP1PARP10FFAR1
SCHEMBL3079739 0.84 RELA (0.50) SRD5A2
SCHEMBL3079740 0.84 RELA (0.50) SRD5A2
SCHEMBL3080310 0.82 MAOB (0.61) MAOACA1CA2GSTP1CA9
SCHEMBL11592340 0.82 LTA4H (0.52) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9136036-B2 Injection moldable, thermoplastic composite materials Miller Waster Mills (US) 2015-09-15 US claimed
EP-2328978-A2 INJECTION MOLDABLE, THERMOPLASTIC COMPOSITE MATERIALS Miller Waste Mills D/b/a Rtp Company (US) 2011-06-08 EP claimed
WO-2010002546-A2 INJECTION MOLDABLE, THERMOPLASTIC COMPOSITE MATERIALS Miller Waste Mills d/b/a RTP Company (US) 2010-01-07 WO claimed
US-20100003438-A1 INJECTION MOLDABLE, THERMOPLASTIC COMPOSITE MATERIALS Miller Waste Mills d/b/a RTP Company 2010-01-07 US claimed
EP-2328978-B1 INJECTION MOLDABLE, THERMOPLASTIC COMPOSITE MATERIALS MILLER WASTE MILLS D B A RTP COMPANY (US) 2016-07-20 EP disclosed
US-9136036-B2 Injection moldable, thermoplastic composite materials Miller Waster Mills (US) 2015-09-15 US disclosed
US-9000084-B2 Controlled geometry composite micro pellets for use in compression molding MILLER WASTE MILLS (US) 2015-04-07 US disclosed
US-8663524-B2 Controlled geometry composite micro pellets for use in compression molding MILLER WASTE MILLS (US) 2014-03-04 US disclosed
US-20120009421-A1 CONTROLLED GEOMETRY COMPOSITE MICRO PELLETS FOR USE IN COMPRESSION MOLDING Miller Waste Mills d/b/a/ RTP Company 2012-01-12 US disclosed
EP-2328978-A2 INJECTION MOLDABLE, THERMOPLASTIC COMPOSITE MATERIALS Miller Waste Mills D/b/a Rtp Company (US) 2011-06-08 EP disclosed
US-20100291388-A1 CONTROLLED GEOMETRY COMPOSITE MICRO PELLETS FOR USE IN COMPRESSION MOLDING Miller Waste Mills d/b/a/ RTP Company 2010-11-18 US disclosed
WO-2010132066-A1 CONTROLLED GEOMETRY COMPOSITE MICRO PELLETS FOR USE IN COMPRESSION MOLDING Miller Waste Mills d/b/a RTP Company (US) 2010-11-18 WO disclosed
EP-0744405-B1 Cyclic peptide antifungal agents LILLY CO ELI (US) 2003-07-16 EP disclosed
EP-0736541-B1 Cyclic hexapeptide antifungal agents LILLY CO ELI (US) 2002-11-27 EP disclosed
US-5652213-A CYCLIC HEXAPEPTIDE FUNGICIDES, PARASITICIDES ELI LILLY AND COMPANY (US) 1997-07-29 US disclosed
US-5646111-A Cyclic peptide antifungal Agents ELI LILLY AND COMPANY (US) 1997-07-08 US disclosed
WO-1996037510-A1 CYCLIC PEPTIDE ANTIFUNGAL AGENTS ELI LILLY AND COMPANY (US) 1996-11-28 WO disclosed
EP-0744405-A2 Cyclic peptide antifungal agents ELI LILLY AND COMPANY (US) 1996-11-27 EP disclosed
WO-1996031228-A1 CYCLIC PEPTIDE ANTIFUNGAL AGENTS ELI LILLY AND COMPANY (US) 1996-10-10 WO disclosed
EP-0736541-A1 Cyclic hexapeptide antifungal agents ELI LILLY AND COMPANY (US) 1996-10-09 EP disclosed