SCHEMBL8880210

SCHEMBL8880210

O=C(O)c1ccc2c(c1)Sc1ccccc1NC2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.62
HPGD P15428 1/20 0.53
MAPT P10636 8/20 0.50
NOX1 Q9Y5S8 5/20 0.50
GAA P10253 5/20 0.50
MEN1 O00255 2/20 0.50
ALOX15 P16050 2/20 0.50
SNCA P37840 2/20 0.50
KMT2A Q03164 2/20 0.50
CYBB P04839 1/20 0.50
APP P05067 1/20 0.50
NOX3 Q9HBY0 1/20 0.50
NOX4 Q9NPH5 1/20 0.50
TP53 P04637 6/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
RXFP1 Q9HBX9 2/20 0.48
POLB P06746 5/20 0.46
KDM4E B2RXH2 2/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11389792 0.89 L3MBTL1 (0.62) L3MBTL1HPGDMAPTNOX1GAA
SCHEMBL23094972 0.88 HPGD (0.55) L3MBTL1HPGDMAPTNOX1GAA
SCHEMBL11390726 0.87 L3MBTL1 (0.60) L3MBTL1HPGDMAPTNOX1GAA
SCHEMBL11396667 0.87 L3MBTL1 (0.60) L3MBTL1HPGDMAPTNOX1GAA
SCHEMBL4670438 0.86 HPGD (0.70) L3MBTL1HPGDMAPTNOX1GAA
SCHEMBL11396917 0.84 TP53 (0.61) L3MBTL1HPGDMAPTNOX1GAA
SCHEMBL29441686 0.83 HPGD (0.51) L3MBTL1HPGDMAPTNOX1GAA
SCHEMBL17085845 0.83 HPGD (0.51) L3MBTL1HPGDMAPTNOX1GAA
SCHEMBL5121603 0.83 NOX1 (0.60) L3MBTL1MAPTNOX1GAAMEN1
SCHEMBL11390619 0.81 L3MBTL1 (0.49) L3MBTL1HPGDMAPTNOX1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4263207-A ANTIALLERGENS MERCK & CO., INC. (US) 1981-04-21 US claimed
US-20210017294-A9 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2021-01-21 US disclosed
US-20210017294-A9 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2021-01-21 US disclosed
EP-3305784-B1 HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS JANSSEN PHARMACEUTICA NV (BE) 2020-08-12 EP disclosed
EP-3305784-B1 HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS JANSSEN PHARMACEUTICA NV (BE) 2020-08-12 EP disclosed
EP-3663317-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF Janssen Pharmaceutica NV (BE) 2020-06-10 EP disclosed
EP-3385284-B1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2020-02-26 EP disclosed
EP-3385284-B1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2020-02-26 EP disclosed
US-20200040107-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2020-02-06 US disclosed
US-20200040107-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2020-02-06 US disclosed
EP-2888286-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF Ortho-Clinical Diagnostics Inc (US) 2015-07-01 EP disclosed
US-20140221616-A1 HAPTENS OF QUETIAPINE ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2014-08-07 US disclosed
US-20140221616-A1 HAPTENS OF QUETIAPINE ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2014-08-07 US disclosed
US-20140221616-A1 HAPTENS OF QUETIAPINE ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2014-08-07 US disclosed
US-20140057305-A1 Antibodies to Quetiapine Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 US disclosed
US-20140057305-A1 Antibodies to Quetiapine Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 US disclosed
US-20140057305-A1 Antibodies to Quetiapine Haptens and Use Thereof JANSSEN PHARMACEUTICA NV (BE) 2014-02-27 US disclosed
WO-2014031665-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF ORTHO-CLINICAL DIAGNOSTICS, INC (US) 2014-02-27 WO disclosed
US-5607929-A Antiviral dibenzothiazepinone derivatives GLAXO WELLCOME INC. (US) 1997-03-04 US disclosed
US-4263207-A ANTIALLERGENS MERCK & CO., INC. (US) 1981-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140057305-A1 Antibodies to Quetiapine Haptens and Use Thereof HTR4, HTR3C, SLC6A4 L3MBTL1 2785/4885HPGD 2037/4885MAPT 1638/4885
US-20200040107-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF HTR4, HTR3C, SLC6A4 L3MBTL1 2785/4885HPGD 2037/4885MAPT 1638/4885
US-20210017294-A9 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF HTR4, HTR3C, SLC6A4 L3MBTL1 2785/4885HPGD 2037/4885MAPT 1638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.