Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900329 | 0.81 | LMNA (0.48) | TSHRLMNACA1FAAH | |
| SCHEMBL8569409 | 0.79 | ALDH1A1 (0.37) | LMNACA1 | |
| SCHEMBL18098080 | 0.79 | CA1 (0.36) | TSHRLMNACA1FAAHBLM | |
| SCHEMBL7223143 | 0.79 | CA1 (0.55) | LMNACA1FAAH | |
| SCHEMBL127947 | 0.78 | TSHR (0.42) | TSHRLMNACA1 | |
| SCHEMBL23048410 | 0.78 | CPB2 (0.42) | TSHRLMNACA1 | |
| SCHEMBL28311582 | 0.78 | LMNA (0.55) | LMNACA1FAAH | |
| Hydrochloric Acid SCHEMBL28164871 | 0.78 | CA1 (0.53) | LMNACA1FAAH | |
| SCHEMBL7218183 | 0.78 | LMNA (0.55) | LMNACA1FAAH | |
| SCHEMBL7854404 | 0.76 | CA1 (0.38) | TSHRLMNACA1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691341-A | ANTILEUKEMIA AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5464833-A | Anticarcinogenic agents, antiretrovirus agents or autoimmune diseases | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0623598-A1 | APOPTOSIS REGULATOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |