SCHEMBL8880477

SCHEMBL8880477

CSc1ccc([CH]c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
AKR1C3 P42330 1/20 0.50
AKR1C2 P52895 1/20 0.50
AKR1C1 Q04828 1/20 0.50
KMT2A Q03164 6/20 0.49
CYP1A2 P05177 6/20 0.48
CYP1A1 P04798 5/20 0.48
CYP1B1 Q16678 5/20 0.48
MEN1 O00255 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 2/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
MAPT P10636 3/20 0.44
LMNA P02545 1/20 0.44
PTGS2 P35354 2/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11613661 0.90 ALDH1A1 (0.64) ALDH1A1AKR1C3AKR1C2AKR1C1KMT2A
SCHEMBL7567049 0.86 CYP1A1 (0.63) ALDH1A1AKR1C3AKR1C2AKR1C1KMT2A
SCHEMBL7567058 0.86 CYP1A1 (0.63) ALDH1A1AKR1C3AKR1C2AKR1C1KMT2A
SCHEMBL2357484 0.79 ALDH1A1 (0.50) ALDH1A1KMT2ACYP1A2MEN1SMN1; SMN2
SCHEMBL3233599 0.78 NFE2L2 (0.48) ALDH1A1CYP1A2CYP1A1CYP1B1NPC1
Methylphenylsulfide SCHEMBL4902407 0.76
Methylphenylsulfide SCHEMBL27951695 0.76 MAPT (0.53) ALDH1A1AKR1C3AKR1C2AKR1C1KMT2A
Methylphenylsulfide SCHEMBL1332325 0.76
Methylphenylsulfide SCHEMBL27970000 0.76 MAPT (0.53) ALDH1A1AKR1C3AKR1C2AKR1C1KMT2A
Methylphenylsulfide SCHEMBL7584 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5661106-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-08-26 US disclosed