Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 6/20 | 0.64 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | ERN1 | O75460 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 2/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27715902 | 0.89 | CA12 (0.71) | PLAUCA12CA9CA1CA2 | |
| SCHEMBL14898128 | 0.88 | PLAU (0.59) | PLAUCA12CA9CA1CA2 | |
| SCHEMBL68931 | 0.88 | CA12 (0.69) | PLAUCA12CA9CA1CA2 | |
| SCHEMBL67941 | 0.88 | CA12 (0.68) | PLAUCA12CA9CA1CA2 | |
| SCHEMBL29410906 | 0.86 | TSHR (0.67) | PLAUCA12CA9CA1CA2 | |
| SCHEMBL1221576 | 0.86 | TSHR (0.67) | PLAUCA12CA9CA1CA2 | |
| SCHEMBL1661764 | 0.85 | CA12 (0.66) | PLAUCA12CA9CA1CA2 | |
| SCHEMBL514 | 0.85 | CA12 (0.66) | PLAUCA12CA9CA1CA2 | |
| SCHEMBL30443216 | 0.85 | CA12 (0.66) | PLAUCA12CA9CA1CA2 | |
| SCHEMBL3359577 | 0.84 | CA12 (0.65) | PLAUCA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |