Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 7/20 | 0.48 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426931 | 0.79 | NPC1 (0.53) | OTUD7BKDM4EMEN1NPC1MAPT | |
| SCHEMBL8882577 | 0.78 | OTUD7B (0.44) | OTUD7BTDP2MAOAMAOBPGR | |
| SCHEMBL8882372 | 0.74 | MAPT (0.62) | OTUD7BTDP2MAOAMAOBPGR | |
| SCHEMBL7434341 | 0.73 | OTUD7B (0.49) | OTUD7BMAOAMAOBPDE7AALDH1A1 | |
| SCHEMBL4408889 | 0.73 | TDP2 (0.65) | TDP2MAOAMAOBPGRTYRO3 | |
| SCHEMBL17310831 | 0.72 | TDP2 (0.42) | OTUD7BTDP2MAOAMAOBTYRO3 | |
| SCHEMBL15414847 | 0.72 | TDP2 (0.42) | OTUD7BTDP2MAOAMAOBTYRO3 | |
| SCHEMBL4718616 | 0.67 | KDM4E (0.63) | TDP2MAOAMAOBTYRO3NTRK2 | |
| SCHEMBL15415003 | 0.67 | TDP2 (0.40) | OTUD7BTDP2MAOAMAOBPGR | |
| SCHEMBL3310832 | 0.67 | MAOB (0.58) | OTUD7BMAOAMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679671-A | ANGIOTENSIN 1-CONVERTING ENZYME INHIBITOR, VASOPRESSIN ANTAGONISM AND ATRIAL NAUTRIURETIC PEPTIDE HYDROLASE INHIBITOR | EISAI CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0671172-A1 | AMINO ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-09-13 | — | — | EP | disclosed |