Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 2/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000781 | 0.84 | OTUD7B (0.50) | OTUD7BSRCHTR5APDE7APDE3B | |
| SCHEMBL7430923 | 0.78 | ALDH1A1 (0.49) | OTUD7BSRCHTR5APDE7APDE3B | |
| SCHEMBL703728 | 0.76 | MAOB (0.58) | PDE3BPDE3AEIF2AK2MAOBMAOA | |
| SCHEMBL29724095 | 0.76 | MAOB (0.58) | PDE3BPDE3AEIF2AK2MAOBMAOA | |
| SCHEMBL1513178 | 0.74 | MAPT (0.53) | HTR5APDE7APDE3BPDE3AEIF2AK2 | |
| SCHEMBL16896923 | 0.74 | OTUD7B (0.55) | OTUD7BSRCHTR5APDE7APDE3B | |
| SCHEMBL8880893 | 0.73 | OTUD7B (0.48) | OTUD7BPDE7AALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL5999174 | 0.73 | PDE3B (0.59) | OTUD7BSRCHTR5APDE7APDE3B | |
| SCHEMBL7426931 | 0.73 | NPC1 (0.53) | OTUD7BSRCALDH1A1THRBMAPK1 | |
| SCHEMBL9405637 | 0.72 | DRD2 (0.49) | OTUD7BSRCHTR5APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4575503-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1986-03-11 | — | — | US | disclosed |
| US-4473575-A | ANGIOTENSIN INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |
| US-4410520-A | ANGIOTENSION CONVERTING ENZYME INGIBITOR, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-10-18 | — | — | US | disclosed |
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |