Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.70 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.70 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.70 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacin SCHEMBL29047499 | 0.88 | ALDH1A1 (0.84) | GAAALDH1A1APPHCAR3HCAR2 | |
| Trolamine SCHEMBL28395110 | 0.85 | F7 (0.71) | GAAALDH1A1APPHCAR3HCAR2 | |
| Niacin SCHEMBL29047503 | 0.84 | ALDH1A1 (0.78) | GAAALDH1A1APPHCAR3HCAR2 | |
| SCHEMBL13562578 | 0.84 | PLOD2 (0.53) | GAAALDH1A1APPHCAR3HCAR2 | |
| Niacin SCHEMBL30844065 | 0.84 | — | — | |
| Niacin SCHEMBL29396199 | 0.84 | ALDH1A1 (1.00) | GAAALDH1A1APPHCAR3HCAR2 | |
| Niacin SCHEMBL3081560 | 0.84 | ALDH1A1 (1.00) | GAAALDH1A1APPHCAR3HCAR2 | |
| Niacin SCHEMBL29349574 | 0.84 | — | — | |
| Niacin SCHEMBL1433 | 0.84 | — | — | |
| Niacin SCHEMBL28292236 | 0.84 | ALDH1A1 (1.00) | GAAALDH1A1APPHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150037394-A1 | DRUG DELIVERY FORMULATIONS | KING'S COLLEGE LONDON | 2015-02-05 | — | — | US | disclosed |
| EP-2723318-A2 | DRUG DELIVERY FORMULATIONS | King's College London (GB) | 2014-04-30 | — | — | EP | disclosed |
| WO-2012175996-A2 | DRUG DELIVERY FORMULATIONS | KING'S COLLEGE LONDON (GB) | 2012-12-27 | — | — | WO | disclosed |
| US-5658576-A | Method for combatting cellulitis or reducing localized fatty excesses | L'OREAL (FR) | 1997-08-19 | — | — | US | disclosed |
| US-5376374-A | Cayenne pepper, calendula, echinacea, goldenseal, propolis, vinegar and water; alleviates gum disease | ZELAYA LUZ M (US) | 1994-12-27 | — | — | US | disclosed |
| US-4795638-A | RUBEFACIENT, PLANT EXTRACT, POLYSILOXANE | L'OREAL (FR) | 1989-01-03 | — | — | US | disclosed |