Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821287 | 0.82 | CA2 (0.44) | CA1CA2NAAATSHR | |
| SCHEMBL27814945 | 0.81 | NAAA (0.39) | NAAA | |
| SCHEMBL247701 | 0.80 | CA2 (0.44) | CA1CA2TSHRUSP2 | |
| SCHEMBL29614 | 0.79 | TP53 (0.31) | — | |
| SCHEMBL4631695 | 0.78 | CA2 (0.40) | CA1CA2NAAATSHRUSP2 | |
| SCHEMBL2180359 | 0.78 | — | — | |
| SCHEMBL4435955 | 0.78 | — | — | |
| SCHEMBL11830727 | 0.77 | OR51E2 (0.39) | — | |
| SCHEMBL11662121 | 0.76 | MGAM (0.46) | CA1CA2NAAATSHRUSP2 | |
| SCHEMBL7057332 | 0.76 | ALDH1A1 (0.46) | CA1CA2NAAATSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110280970-A1 | ABSORBABLE PUTTY-LIKE IMPLANTS AND METHODS FOR THEIR USE FOR MECHANICAL HEMOSTASIS OF BONE AND FOR THE TREATMENT OF OSSEOUS DEFECTS | ORTHOCON, INC. (US) | 2011-11-17 | — | — | US | claimed |
| EP-1677664-A4 | ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS | ORTHOCON INC (US) | 2009-08-19 | — | — | EP | claimed |
| EP-1677708-A1 | BIOABSORBABLE PUTTY-LIKE HEMOSTATIC IMPLANTS | Orthocon, LLC (US) | 2006-07-12 | — | — | EP | claimed |
| EP-1677664-A2 | ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS | Ortho Therapeutics, LLC. (US) | 2006-07-12 | — | — | EP | claimed |
| US-20060002976-A1 | Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects | ABYRX, INC. | 2006-01-05 | — | — | US | claimed |
| WO-2005034726-A2 | ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS | ORTHO THERAPEUTICS, LLC (US) | 2005-04-21 | — | — | WO | claimed |
| WO-2005034816-A1 | BIOABSORBABLE PUTTY-LIKE HEMOSTATIC IMPLANTS | ORTHO THERAPEUTICS, LLC. (US) | 2005-04-21 | — | — | WO | claimed |
| US-20050065214-A1 | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects | ABYRX, INC. | 2005-03-24 | — | — | US | claimed |
| EP-2462957-A2 | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects | Orthocon Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2462958-A2 | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects | Orthocon Inc. (US) | 2012-06-13 | — | — | EP | disclosed |