Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 2/20 | 0.59 |
| ▸ | CTSK | P43235 | 8/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637193 | 0.90 | CTSK (0.56) | PSMB1CTSKCTSSCTSLCTSB | |
| SCHEMBL29637195 | 0.90 | CTSK (0.56) | PSMB1CTSKCTSSCTSLCTSB | |
| SCHEMBL25182274 | 0.89 | CTSK (0.61) | PSMB1CTSKCTSSCTSLCTSB | |
| SCHEMBL10985006 | 0.87 | CTSK (0.58) | PSMB1CTSKCTSSCTSLCTSB | |
| SCHEMBL10985008 | 0.87 | CTSK (0.58) | PSMB1CTSKCTSSCTSLCTSB | |
| SCHEMBL2724462 | 0.86 | CTSK (0.61) | PSMB1CTSKCTSSCTSLCTSB | |
| SCHEMBL28225820 | 0.86 | CTSK (0.57) | PSMB1CTSKCTSSCTSLCTSB | |
| SCHEMBL5724608 | 0.85 | CTSK (0.62) | PSMB1CTSKCTSSCTSLCTSB | |
| SCHEMBL13074183 | 0.85 | CTSK (0.64) | PSMB1CTSKCTSSCTSLCTSB | |
| SCHEMBL14595271 | 0.85 | CTSK (0.64) | PSMB1CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672598-A | MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |