Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985006 | 1.00 | CTSK (0.58) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL10966776 | 0.90 | CTRB1 (0.61) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL25182274 | 0.89 | CTSK (0.61) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL8881595 | 0.87 | PSMB1 (0.59) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL79250 | 0.86 | CTRB1 (0.57) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL14530318 | 0.86 | SYK (0.60) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL10964829 | 0.86 | CTRB1 (0.57) | CTRB1 | |
| SCHEMBL555191 | 0.86 | CTRB1 (0.57) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL28184491 | 0.86 | CTRB1 (0.68) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL555192 | 0.86 | CTRB1 (0.57) | CTSKCTSSCTSLCTSBCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |