Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.57 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25182274 | 0.88 | CTSK (0.61) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL10985008 | 0.86 | CTSK (0.58) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL8881595 | 0.86 | PSMB1 (0.59) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL10985006 | 0.86 | CTSK (0.58) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL2723504 | 0.84 | CTSK (0.62) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL13074183 | 0.84 | CTSK (0.64) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL14595271 | 0.84 | CTSK (0.64) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL5724608 | 0.84 | CTSK (0.62) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL14923444 | 0.84 | CTSK (0.62) | CTSKCTSSCTSLCTSBCTRB1 | |
| SCHEMBL29637193 | 0.84 | CTSK (0.56) | CTSKCTSSCTSLCTSBCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108164583-A | Proteasome inhibitor and its application | 珠海诺贝尔国际生物医药研究院有限公司 | 2018-06-15 | — | — | CN | disclosed |