SCHEMBL888164

SCHEMBL888164

CC1CCC(C(C)C)C(OCCOCCO)C1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.45
APOBEC3A P31941 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
GAA P10253 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TRPA1 O75762 2/20 0.42
TRPM8 Q7Z2W7 2/20 0.42
P2RX4 Q99571 1/20 0.42
NTSR1 P30989 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
EPHX1 P07099 3/20 0.41
HPGD P15428 1/20 0.40
MAPT P10636 1/20 0.40
CYP19A1 P11511 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23196491 1.00 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL29230105 1.00 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL12715399 1.00 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL7068032 1.00 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1616052 0.94 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1617841 0.93 ALDH1A1 (0.58) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1616025 0.93 ALDH1A1 (0.58) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL28140415 0.92 ALDH1A1 (0.69) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL3388061 0.91 ALDH1A1 (0.67) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL12086406 0.91 ALDH1A1 (0.67) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3817575-B1 SOLUBILISATION OF COOLING AGENTS OF LOW SOLUBILITY SYMRISE AG (DE) 2025-10-15 EP claimed
EP-4583718-A1 FLAVONOID COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2025-07-16 EP claimed
WO-2025132323-A1 COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT DSM-FIRMENICH AG (CH) 2025-06-26 WO claimed
CN-120129464-A Flavonoid compound and application thereof 弗门尼舍有限公司 2025-06-10 CN claimed
EP-4251122-B1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2025-03-12 EP claimed
US-20240238183-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2024-07-18 US claimed
WO-2024088925-A1 FLAVONOID COMPOSITIONS AND USES THEREOF FIRMENICH SA (CH) 2024-05-02 WO claimed
US-20240058238-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2024-02-22 US claimed
CN-117479843-A Composition for enhancing cooling effect 弗门尼舍公司 2024-01-30 CN claimed
EP-4304385-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT Firmenich Incorporated (US) 2024-01-17 EP claimed
WO-2021071898-A1 FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS BEDOUKIAN RESEARCH, INC. (US) 2021-04-15 WO claimed
WO-2021071896-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS BEDOUKIAN RESEARCH, INC. (US) 2021-04-15 WO claimed
WO-2020007484-A1 SOLUBILIZATION OF POORLY SOLUBLE COOLING SUBSTANCES SYMRISE AG (DE) 2020-01-09 WO claimed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 US claimed
US-20150087856-A1 MELANIN PRODUCTION INHIBITOR TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-03-26 US claimed
EP-2725900-A1 ANTIMICROBIAL COMPOSITION Takasago International Corporation (JP) 2014-05-07 EP claimed
WO-2013002421-A1 ANTIMICROBIAL COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-01-03 WO claimed
US-20130005807-A1 ANTIMICROBIAL COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-01-03 US claimed
US-20110281945-A1 GASTRIC ACID SECRETION INHIBITOR, AND POTASSIUM CHANNEL INHIBITOR SHIZUOKA PREFECTURE PUBLIC UNIVERSITY CORPORATION (JP) 2011-11-17 US claimed
US-20100216876-A1 ANTIDIARRHETIC COMPOSITION, PRODUCT CONTAINING THE SAME AND METHOD OF PREVENTING DIAHHREA TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-08-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 ALDH1A1 3726/4885LMNA 3784/4885KDM4E 4171/4885
US-20150087856-A1 MELANIN PRODUCTION INHIBITOR TYR, MITF, MC1R ALDH1A1 926/4885LMNA 4533/4885KDM4E 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.