Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882405 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2GLATACR3HTTMAPT | |
| SCHEMBL8885186 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2GLATACR3HTTALDH1A1 | |
| SCHEMBL8885183 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2GLATACR3HTTMAPT | |
| SCHEMBL4313304 | 0.74 | TACR3 (0.41) | TACR3ALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL3623844 | 0.72 | TACR3 (0.37) | TACR3KDM4EKMT2AL3MBTL1CNR2 | |
| SCHEMBL8883099 | 0.69 | TAS1R3 (0.39) | TACR3KDM4EKMT2AL3MBTL1CNR2 | |
| SCHEMBL28175896 | 0.68 | ALDH1A1 (0.39) | MAPTALDH1A1CYP1A2CYP3A4GSR | |
| SCHEMBL5013693 | 0.68 | KDM4E (0.41) | TACR3KDM4EKMT2AL3MBTL1CNR2 | |
| SCHEMBL11617237 | 0.67 | PLK1 (0.48) | TACR3ALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL28645727 | 0.67 | CDK2 (0.43) | GLAALDH1A1CYP3A4KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650513-A | Process for preparing perylene-3,4-dicarboxylic acid derivatives, the derivatives thus prepared and their use | CIBA-GEIGY CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |